日本語
Ingenol-3-angelate (CAS 75567-37-2), also known as PEP005 or Ingenol mebutate, is a diterpene ester derived from Euphorbia peplus. It is a potent Protein Kinase C (PKC) activator widely studied for its anticancer, pro-apoptotic, and immunomodulatory activities. We supply ≥98% high-purity research grade Ingenol-3-angelate with COA, HPLC, MSDS, and worldwide shipping support, suitable for pharmaceutical, biomedical, and natural product research.
製品名 :
Ingenol-3-angelateCAS番号 :
75567-37-2外観 :
Fine White Powder仕様 :
98%Product Name: Ingenol-3-angelate
Synonyms: Ingenol mebutate; PEP005; Euphorbia diterpene ester
CAS Number: 75567-37-2
Molecular Formula: C25H34O6
Molecular Weight: 430.53 g/mol
Appearance: White to off-white powder
Source: Derived from Euphorbia peplus (Spurge)
Category: Natural diterpene ester / Bioactive compound
🌿 What is Ingenol-3-angelate?
Ingenol-3-angelate (CAS: 75567-37-2), also known as PEP005 or Ingenol mebutate, is a semi-synthetic diterpene ester originally isolated from the plant Euphorbia peplus.
It is a potent Protein Kinase C (PKC) activator, widely studied for its anticancer, pro-apoptotic, immunomodulatory, and antiviral activities.
As a bioactive natural product, Ingenol-3-angelate has been applied in cancer biology, immunology, and drug discovery research. It has also been investigated in clinical studies for the treatment of actinic keratosis and other dermatological conditions.
We provide high-purity Ingenol-3-angelate (≥98%) for scientific research and industrial applications.
🔬 Ingenol-3-angelate 98% (Research Grade)
💎 High Purity: ≥98% verified by HPLC
🔬 Research Grade: Suitable for pharmaceutical, biomedical, and natural product studies
🌿 Multiple Bioactivities: PKC activation, anticancer, pro-apoptotic, and immunomodulatory effects
📑 Technical Support: COA, HPLC chromatograms, MS, and NMR data available
Pharmaceutical Research: Studied for its role in skin disease treatments and cancer therapy.
Biomedical Studies: Applied in apoptosis, necrosis, immune response, and signal transduction research.
Immunology & Virology: Explored as an HIV latency-reversing agent and immune activator.
Natural Product Development: A diterpene ester derivative with potential in topical drug delivery systems.
📊 Technical Specifications (98% Grade)
| Item | Specification |
|---|---|
| Product Name | Ingenol-3-angelate |
| CAS Number | 75567-37-2 |
| Molecular Formula | C25H34O6 |
| Molecular Weight | 430.53 g/mol |
| Appearance | White to off-white powder |
| Purity | ≥98% (HPLC) |
| Source | Euphorbia peplus |
| Solubility | Soluble in DMSO, ethanol, chloroform, dichloromethane, ethyl acetate; poorly soluble in water |
| Storage | Store at –20 °C, dry and protected from light |
| Shelf Life | 24 months under proper storage conditions |
🌟 Why Choose Us?
✅ Professional manufacturer & supplier of natural phytochemicals
✅ Strict quality control with COA, HPLC, MSDS, NMR support
✅ Flexible supply: from milligram to bulk orders
✅ Reliable quality trusted by pharmaceuticals, nutraceuticals, and research institutions
✅ Fast worldwide shipping and stable supply
📦 Packaging & Delivery
Standard Packaging: 20mg,100mg,1g,5g,10g...
Bulk Packaging: Customized quantities available upon request
Fast worldwide shipping with professional logistics support
📩 Order & Contact
Looking for high-quality Ingenol-3-angelate (CAS: 75567-37-2)?
We supply ≥98% research grade material with reliable quality and professional technical support.
🌐 Website: www.cqherb.com
📩 Contact us today for samples, quotations, and technical documents.
シクロパミン 98%（CAS: 4449-51-8）は、ヘッジホッグ経路を標的とする強力なステロイドアルカロイドであり、ICでスムーゼンド（Smo）を選択的に阻害します。50 46 nM。この医薬品グレードの阻害剤は、腫瘍学研究（膵臓がん／基底細胞がん）および幹細胞分化研究において検証されています。
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インゲノールは、天然植物由来の高純度の医薬品中間体です。 当社の製品は99.0%以上の純度と厳格な品質管理を保証し、研究・生産ニーズへの信頼性を確保しています。競争力のある価格設定と柔軟なグローバルロジスティクスにより、お客様の多様なニーズに応えるシームレスなサプライチェーンサポートを提供します。
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天然由来の五環式トリテルペノイド、 ルペオル イチゴ、マンゴー、伝統的なハーブなどの植物源から抽出されます。 当社の Lupeol は HPLC 純度が 99% を超えており、研究および製造に関する厳格な医薬品基準を満たしています。
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クルクリゴシド クルクリゴ属から単離された高純度のフェノール配糖体で、その強力な生理活性から薬理研究において広く利用されています。HPLCによる純度確認では98%以上であり、創薬および作用機序研究における重要な標準物質として用いられています。
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ホルボール 12-ミリスチン酸 13-酢酸 (PMA) 98% (CAS:16561-29-8) は、クロトン・ティグリウム種子由来の超高純度結晶性PKC活性化剤で、腫瘍形成および免疫学研究への応用が検証されています。HPLCで98%以上の純度が検証されており、DMBA誘導性発がんモデルから好中球NETosis研究に至るまで、1～100 nMの濃度でPKC依存性経路を確実に誘導します。
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